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Pharmacokinetics of intravenous and oral metformin and r,s-verapamil in Sinclair, Hanford, Yucatan and Göttingen minipigs

Pharmacokinetics of intravenous and oral metformin and r,s-verapamil in Sinclair, Hanford, Yucatan and Göttingen minipigs

Mar 26, 2019 | White Papers

Introduction Oral and intravenous pharmacokinetic (PK) studies were conducted in four different minipig strains: Sinclair, Yucatan, Hanford and Göttingen after administration of metformin or R,S-verapamil (R,S-VER). Results: The results indicated that the PK...
Characterization of Transdermal Pharmacokinetics of Ketoprofen in Sinclair and Gottingen Minipigs

Characterization of Transdermal Pharmacokinetics of Ketoprofen in Sinclair and Gottingen Minipigs

Mar 13, 2019 | Scientific Posters

Abstract Purpose: To characterize transdermal pharmacokinetics of a ketoprofen cream formulation in the Sinclair and Gӧttingen strains of minipigs. Methods: Sinclair and Gӧttingen minipigs (3 per gender of each strain) were used in this study. Four mL of...

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