Portal Vein Catheterization in Swine

Portal Vein Catheterization in Swine

Introduction The portal vein may be catheterized to administer test substances free of the digestive processes or to withdraw blood samples prior to hepatic metabolism as well as blood flow studies. A complete description of the various techniques of catheterization...
Common Bile Duct Cannulation in Swine

Common Bile Duct Cannulation in Swine

Introduction Bile duct cannulation is most frequently performed to study hepatic metabolism and secretion of pharmaceuticals in swine. The bile duct must be cannulated in a re-entry fashion for experiments longer than a few days, otherwise pathology due to a lack of...
Nonsurgical Vascular Catheterization Techniques in Swine

Nonsurgical Vascular Catheterization Techniques in Swine

Introduction Collection of blood and intravascular administration of test substances is one of the most common procedures required in preclinical trials of therapeutic agents. Comprehensive descriptions of the various IV sites and the surgical approaches for chronic...