Mar 14, 2019 | Scientific Posters
Abstract The Sinclair miniature swine (SMS) is the oldest strain of miniature swine developed for research; it is one of the smallest as well. In an effort to generate a database of baseline information about the normal physiological status of the SMS, information was...
Mar 14, 2019 | Scientific Posters
Abstract In an effort to further support biomedical research, we recently updated a comprehensive dataset on normal data (reference intervals or ranges) for our four lineages of miniature swine. Included are Yucatan, Hanford, Sinclair S-1, and Micro-Yucatan lineages....
Mar 13, 2019 | Scientific Posters
Abstract Introduction: Skin is the largest organ in the body. Animals have skin which is generally similar to human skin, however, species specific anatomical and biochemical differences exist. The integument of animal models may vary in skin surface topography,...
Mar 13, 2019 | Scientific Posters
Abstract Swine have been used extensively in research because of correlated similarities to humans. Miniature swine offer many distinct advantages for researchers but reference normal data is sometimes lacking for miniswine. In an effort to generate a database on...
Mar 13, 2019 | Scientific Posters
Abstract Dermatology is an extremely important field as the skin of humans and animals plays a life sparing protective role. The skin is the largest organ of the body and is metabolically active. Skin is constantly undergoing changes of shedding and regeneration. Skin...
Mar 13, 2019 | Scientific Posters
Abstract The miniature swine have been increasingly recognized as a non-rodent model in regulatory toxicity. Members of the FDA have even published on the use of miniature swine as an alternative to canine and non-human primates in regulatory toxicity. The...
Mar 12, 2019 | Scientific Posters
Abstract The miniature swine are increasingly recognized as a non-rodent model for regulatory toxicity studies. For the use of the miniature swine in toxicology, it is critical to develop a central database of background or “normal” histopathological findings. In a...
Mar 8, 2019 | Scientific Posters
Abstract Process drift occurs when a procedure becomes altered as it is passed down through laboratory personnel. Reviewing and changing procedures can provide quality benefits and significantly improve processes and animal welfare. Quality benefits include reducing...
Feb 22, 2019 | Scientific Posters
Abstract Miniature swine have many advantages over other species for biomedical research such as their anatomical and physiological similarities to humans. However, one of the disadvantages of the miniature swine for biomedical research such as harmaceutical...
Feb 22, 2019 | Scientific Posters
Abstract Acute dermal irritation was induced and characterized in white Sinclair and Hanford minipigs (N = 2 per breed per study, 3-4 months old, all females) using a variety of known human irritants at increasing concentrations, as two pilot studies (single dose and...