Pharmacokinetics

Sinclair Research specializes in conducting pharmacology and pharmacokinetics (PK studies), especially in miniature swine:

  • Our resident scientists are experts in conducting in-life PK studies
  • We utilize outside experts for analytical, kinetic, and PK statistical analyses and modeling phases
  • PK studies are offered for many species of animals; we have experience with NHP, canine, miniature swine, rabbit, and rodent PK studies
  • We offer stock animal colonies to sponsors to facilitate rapid testing of multiple formulations, isomers, or analogues

Pharmacokinetics / Pharmacodynamics

Services offered include:  

  • Plasma drug profiles following most routes of administration
  • Dynamic change in blood glucose or other biomarker or physiological parameters
  • Global dog, NHP, and pig protocols, compounds, or formulations tested weekly for timely feedback
  • Specialized PK studies for bridging active pharmaceutical ingredient (API) compounds
  • Cerebrospinal fluid (CSF) drug levels

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