Orthopedic and Cartilage Models

Authors

Sinclair Research Center

Introduction

Osteoarthritis, cartilage and bone repair, and osteoporosis are research offerings at Sinclair Research. Sinclair Research offers 16 animal species as models for use in these protocols. Both non-regulatory and GLP studies, in large and small animal models are routine. Articular cartilage studies in sheep have included preclinical GLP assessments, including stem-cell therapy. A veterinary surgeon and three clinical veterinarians support these programs. Sinclair Research also utilizes outside expert surgical interventionalists who specialize in orthopedic studies. An independent consultant expert in orthopedic models is available for study design/protocol development and in-life study auditing on large, complex and expensive studies.

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