Hanford Labs started developing the Hanford miniature swine in 1958 in Richland, WA with two Palouse gilts and one Pittman-Moore boar; later addition of more Pittman-Moore and Swamp hog from Louisiana further reduced the size.
Selection occurred at 140 days of age for fitness, skin and hair color, conformation, thickness of hair coat, and demeanor.
Battelle Memorial Institute acquired the herd in the mid-1960’s and introduced Yucatan into the foundation stock.
Charles River Laboratories assumed the breeding of the Hanford in 1982 at Wilmington, MA.
The colony was moved to Pittsfield, NH in 1983.
Sinclair BioResources acquired the Hanford herd in 2002 and moved the colony to Columbia, MO.
The colony is closed and fully-pedigreed
Well-adapted to the laboratory environment
Looks like traditional farm pigs
Used predominantly as a dermal toxicology model
White skin and haircoat make them excellent for dermal studies
Lack of fat makes them a good model for surgical studies
Heart size and collateral blood flow very similar to human hearts makes them an excellent cardiovascular mode