Hanford Miniature Swine

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Background

  • Hanford Labs started developing the Hanford miniature swine in 1958 in Richland, WA with two Palouse gilts and one Pittman-Moore boar; later addition of more Pittman-Moore and Swamp hog from Louisiana further reduced the size
  • Selection occurred at 140 days of age for fitness, skin and hair color, conformation, thickness of hair coat, and demeanor
  • Battelle Memorial Institute acquired the herd in the mid-1960’s and introduced Yucatan into the foundation stock
  • Charles River Laboratories assumed the breeding of the Hanford in 1982 at Wilmington, MA
  • The colony was moved to Pittsfield, NH in 1983
  • Sinclair BioResources acquired the Hanford herd in 2002 and moved the colony to Columbia, MO
  • The colony is closed and fully pedigreed

Characteristics

  • Well-adapted to the laboratory environment
  • Looks like traditional farm pigs
  • Used predominantly as a dermal toxicology model
  • White skin and haircoat make them excellent for dermal studies
  • Lack of fat makes them a good model for surgical studies
  • Heart size and collateral blood flow very similar to human hearts makes them an excellent cardiovascular model

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