Auditory Research
Turner Scientific
Turner Scientific serves as Sinclair’s niche expert in auditory and vestibular research, offering our sponsors the ability to evaluate their compounds, therapies, and devices for efficacy and potential for ototoxicity. We have a seamless relationship whereby Turner Scientific provides the otic-specific support, communication, and expertise for sponsors seeking GLP and/or small species hearing testing. Leveraging Turner Scientific’s expertise, we use ABR/DPOAE assessments and behavioral audiometry to evaluate hearing and tinnitus, and harvest temporal bones to quantify hair cells and ribbon synapses using confocal laser microscopy (cytocochleograms).
Discovery Pharmacology
Bolder BioPATH
Bolder BioPATH, a Colorado-based provider of pharmacology and pathology services, specializes in in vivo models of Rheumatoid Arthritis, Osteoarthritis, Inflammatory Bowel Disease, and other autoimmune and inflammation models. The addition of Bolder BioPATH’s pharmacology model portfolio and expertise to Sinclair’s growing nonclinical toxicology services is an excellent strategic fit and enables us to support customers earlier in the development process on their way toward critical IND-enabling studies.
Safety Pharmacology
CorDynamics
CorDynamics specializes in cardiovascular drug discovery, toxicology and safety pharmacology evaluation. Sinclair Research has acquired the GLP Safety Pharmacology business unit from CorDynamics to offer sponsors GLP cardiopulmonary safety pharmacology studies at our site. We have an ongoing partnership with the cardiovascular research experts at CorDynamics to provide our sponsors with review, analysis, and interpretation of the data generated in Safety Pharmacology studies as well as access to a vast library of cardiovascular drug discovery models including heart failure, pulmonary arterial hypertension and atrial fibrillation.
Bioanalytical Services
Royalmount Laboratories
Royalmount Laboratories, a division of Pharmascience Inc., specializes in bioanalytical services providing sponsors with bioanalytical method development, validation and quantitation of drugs and metabolites in biological matrices. Our two companies work together to offer a seamless experience for Sinclair Research sponsors, providing access to bioanalytical expertise and efficient bioanalytical services.