What is the Veterinary Oral Health Council (VOHC)?
What is the VOHC Seal of Acceptance?
Who Can Benefit From the VOHC Seal?
How to Apply for the VOHC Seal
Pre-study communication with the VOHC should start as early as possible, and all study protocols should be provided to the VOHC for review and concurrence before study initiation. This ensures an acceptable study design is used and any product-specific considerations are addressed. Contact our team to introduce you to the VOHC.
What is Required in a VOHC Study Program?
- Study conduct following good scientific practices, the Animal Welfare Act, the VOHC approved protocol, and the facility SOPs.
- The VOHC requires two trials with the product, to insure repeatability of results. Animals used in the first trial cannot be used in a second trial.
- Study conduct in healthy animals in the species for which the product will be used.
- Study conducted in animals having a designated set of teeth termed “VOHC Teeth” that are intact, with normal occlusion, and are healthy.
- The studies use the “clean mouth model” in which teeth are scaled and polished at the start of the trial, so there is no plaque or calculus present. The studies are evaluating the PREVENTION of plaque and calculus formation, not the ability to remove plaque and calculus that is already established.
- Study conduct must employ personnel that are trained and experienced scoring teeth in dental studies. This experience must be described in the protocol.
- The study should be randomized, controlled (placebo or negative control), and masked (personnel scoring teeth must be blinded to treatment).
- If the product contains a chemical anti-plaque or anti-calculus agent, evidence must be provided that the agent is safe, in addition to the efficacy data.
- Products having both chemical and mechanical action will require an additional treatment group.
You can view full study design requirements on the “Protocol and Submissions” page on the VOHC website.
Laboratory Essentials for Your VOHC Study Program
Perhaps the single most important factor in the success of a VOHC program is the experience of the performing laboratory. The laboratory conducting the study must have significant experience with the evaluation of dental efficacy in dogs and cats. Sinclair has conducted dozens of studies for VOHC submission, and Sinclair data has supported many seal awards.
Experienced Veterinary Dental Professionals
The experience of the person scoring the teeth during studies is of utmost importance. Sinclair is proud to work with consulting veterinary dental professionals with many years of experience scoring teeth for the VOHC.
Have a question? Contact us today!
Choosing a CRO for your study can be a daunting task. Our scientific experts are standing by to help with any questions you may have. Just click or tap the button below to start and we will contact you within a couple of hours.