Orthopaedic Surgical Services
Sinclair Research Center provides orthopaedic surgical capabilities and services ranging from simple to complex orthopaedic procedures. Whether supporting the development of a new orthopaedic device or treatment, SRC’s unique combination of technology, facilities and experience provide our clients with all the right tools. Representative capabilities include:
Joint/Cartilage Models
- Articular Cartilage Repair
- ACL Repair
- OA Models
- Meniscal Repair
- Reconstruction/Fixation of Ligaments/Tendon
Bone Fracture/Defect Repair Models
- Critical/Non-Critical Segmental Defects
- Tibial/Femoral/Ulnar Osteotomy Models
- Maxillofacial/Mandibular Defects
- Autograft/Allograft/Bone Graft Substitutes
- Bone Ingrowth for Joint Replacement
- Non-Weight Bearing (Axial, Transcoritcal)
- Bone Cements, Puttys, Etc.
Spinal Fusion and Spinal Instability/Fixation Models
- Spinal Surgery/Bone Reconstruction
- Posterolateral/Interbody Fusion
- Intervertebral Disc Reconstruction
- Discectomy/Disc Replacement
- Spine Intervention
Models of Osteopenia and Trabecular Plate Perforation
- Calcium Restricted Ovariectomized Sinclair Miniature Swine Model
- Sinclair Miniature Swine Adult Osteopenia Model
Spinal Fusion and Spinal Instability/Fixation Models
Facility and Personnel:
- Four Surgical Suites - High Volume Programs
- Network of Consulting Orthopaedic and Device Surgeons
- Experienced In-Vivo Surgical Support Team
- Dedicated Large Animal Necropsy Suite
- Board Certified Veterinary Pathologist
- Network of Experts for All Experimental Phases
Imaging Equipment Including:
- DEXA (Hologic Discovery A)
- Bone Density
- Whole Body Composition
- Fluoroscopy, Angiography, Radiography
- 1.5 Tesla GE Signa Horizon LX MR
- Picker PQ6000 Spiral CT (CT/MR via collaborative agreement with MU Vet School Radiology Lab)
- Color Doppler Ultrasonography
Supporting Sub-Contractors
Histopathology/Histomorhometry:
Plastic Imbedding, Qualitative and Quantitative Analysis, including Fluorochrome Labeled Histomorphometry
- Histion (Dr. Donna Wheeler for Histomorphometry - GLP)
- HSRL (GLP)
- Accellab (GLP)
- MDS (GLP)
- Fellowship of Orthopaedic Researchers (non-GLP)
Mechanical Testing:
- Gustilo Medical Education Center (Non-GLP)(Soft Tissue Mechanical Testing)
- Bone Healing Research Laboratory, University of Iowa College of Medicine (Non-GLP)
- Fellowship of Orthopaedic Researchers (non-GLP)
- Histion (GLP)
- MDS (GLP)